Open AccessThe Use of Extracorporeal Circulation in Suspected Brain Dead Organ Donors with Cardiopulmonary Collapse
Author(s) -
SangDo Lee,
Yang Hyun Cho,
Kiick Sung,
Jeong Hoon Yang,
Chi Ryang Chung,
Kyeongman Jeon,
Gee Young Suh
Publication year - 2015
Publication title -
journal of korean medical science/journal of korean medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.743
H-Index - 66
eISSN - 1598-6357
pISSN - 1011-8934
DOI - 10.3346/jkms.2015.30.12.1911
Subject(s) - medicine , organ donation , extracorporeal membrane oxygenation , cardiopulmonary resuscitation , cardiopulmonary bypass , transplantation , liver transplantation , extracorporeal , economic shortage , extracorporeal circulation , brain dead , lung , organ transplantation , kidney transplantation , organ dysfunction , kidney , surgery , anesthesia , resuscitation , sepsis , linguistics , philosophy , government (linguistics)
Donor shortage is a major limitation in organ transplantation. Several studies have reported that extracorporeal membrane oxygenation (ECMO)-assisted organ donation can be successfully completed without inducing warm ischemia in patients with brain death. The present report described clinical experience of three patients (23-yr old man, 32-yr old man, and 41-yr old woman) who underwent ECMO for the evaluation of brain death and organ donation. They donated six kidneys, three livers, and one both lungs without warm ischemia by ECMO. Six kidney recipients successfully recovered normal status without hemodialysis and two liver recipients survived with normal liver functions, but one liver recipient and one lung recipient died 3 and 15 days after transplantation. Our report strongly encourages ECMO-assisted organ donation from brain death patients with refractory cardiopulmonary collapse to achieve improved organ transplantation.