Open AccessA Case of Hypersensitivity to Mosquito Bite Associated with Epstein-Barr Viral Infection and Natural Killer Cell Lymphocytosis
Author(s) -
Eui Jung Roh,
Eun Hee Chung,
Young Pyo Chang,
Na Hye Myoung,
Young Koo Jee,
Min Seo,
Jin Han Kang
Publication year - 2010
Publication title -
journal of korean medical science/journal of korean medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.743
H-Index - 66
eISSN - 1598-6357
pISSN - 1011-8934
DOI - 10.3346/jkms.2010.25.2.321
Subject(s) - lymphocytosis , immunology , virus , lymphoma , medicine , epstein–barr virus , virology , bone marrow , pathology , biology , natural killer cell , cytotoxic t cell , biochemistry , in vitro
Hypersensitivity to mosquito bites (HMB) is a disorder characterized by a necrotic skin reaction and generalized symptoms subsequent to mosquito bites. It has been suggested that HMB is associated with chronic Epstein-Barr virus (EBV) infection and natural killer cell leukemia/lymphoma. We describe here a Korean child who had HMB associated with chronic EBV infection and natural killer cell lymphocytosis. A 5-yr-old boy was suffered from necrotic skin lesions on the right ear lobe. Type A EB virus was detected from hlood cells and bone marrow biospy recognized hemophagocyrosis.