Open AccessRoutine laboratory parameters of newly diagnosed pulmonary tuberculosis patients: a single center study in Brazil
Author(s) -
Ana Paula Biadola,
André Aparecido dos Santos Correa,
Amanda Aparecida Silva de Aguiar,
Ualter Guilherme Cipriano Rosa,
Paulo José Mascarenhas Mazaro,
Christiane Martinez Húngaro,
Marcus Vinícius Pimenta Rodrigues,
Eliana PeresiLordelo
Publication year - 2020
Publication title -
research, society and development
Language(s) - English
Resource type - Journals
ISSN - 2525-3409
DOI - 10.33448/rsd-v9i11.9873
Subject(s) - medicine , tuberculosis , hypomagnesemia , hyponatremia , gastroenterology , pulmonary tuberculosis , pathology , materials science , magnesium , metallurgy
Objective: Evaluate the severity of tuberculosis and its association with laboratory tests before antituberculosis treatment. Methodology: Patients with pulmonary tuberculosis were evaluated for severity using data available in medical records (Clinical; Excretion of mycobacteria; and Diagnostic imaging) and associated with biochemical and hematological parameters requested at the time of diagnosis and before antituberculosis treatment. Results: The evaluation of the severity showed a predominance of smear AFB (+), fever associated with other symptoms and infiltrative tuberculosis. Only a positive correlation between mycobacteria excretion and imaging diagnosis (rho=0.47; p=0.023) was observed. The patients presented hyponatremia (9/21), hypomagnesemia (6/13), and hypercalcemia (1/13), unrelated to the severity. The presence of fever influenced the number of non-segmented neutrophils (p=0.0142) and the total leukocyte count correlated with the increase in total neutrophils (rho=0.9631; p<0.0001). Conclusion: Different severity characteristics of tuberculosis, although they reflect the degree of commitment of the patient, are not always correlated; the evaluation of electrolytes could contribute to clinical behavior; and non-segmented neutrophils are associated with a worse clinical prognosis in patients with tuberculosis.