Open AccessInga laurina crude extract to control Aedes aegypti
Author(s) -
Elisângela Yumi Sugauara,
Isabelle Luiz Rahal,
Hérika Line Marko de Oliveira,
Wanessa de Campos Bortolucci,
Carla Maria Mariano Fernandez,
Maria Graciela Iecher Faria,
Suelen Pereira Ruiz,
José Eduardo Gonçalves,
Nelson Barros Colauto,
Zilda Cristiani Gazim,
Giani Andréa Linde
Publication year - 2020
Publication title -
research, society and development
Language(s) - English
Resource type - Journals
ISSN - 2525-3409
DOI - 10.33448/rsd-v9i11.9683
Subject(s) - aedes aegypti , phytol , maceration (sewage) , traditional medicine , caryophyllene , chemistry , eugenol , larva , biology , botany , horticulture , essential oil , organic chemistry , medicine , materials science , composite material
Aedes aegypti is the um mosquito responsible for the transmission of several diseases to humans such as dengue, chikungunya, Zika virus and urban yellow fever. The control of this culicid is done by utilizing insecticides that cause insect resistance. Therefore, natural alternatives to control A. aegypti have been sought. Thus, the objective of our work was to characterize the chemical composition of the crude extract of the leaves of Inga laurina and to evaluate the insecticidal activity of the extract on the larvae of A. aegypti. The crude extract was prepared form dry leaves by dynamic maceration using alcohol 96º GL as extracting solvent. The chemical identification of the compounds found in the crude extract was done by a gas chromatography coupled to mass spectrometry. The larvicidal activity was determined by larval packet test in third-stage development larvae A. aegypti. Fifteen compounds were identified in the leaves and the major ones were γ- sitosterol (34.39%), phytol (14.51%), squalene (8.57%) and stigmasterol (7.38%). I. laurina leaf crude extract presented larvicidal activity potential against A. aegypti larvae presenting lethal concentration of 50% (CL50) of 0.98 mg/mL and 99% (CL99) of 2.69 mg/mL. Thus, I. laurina leaf crude extract presented rich composition of phytosterols and promising insecticide activity against A. aegypti larvae, offering new possibilities for the application and development of products.