Open AccessEffects of probiotic supplementation on glucose metabolism and inflammatory biomarkers in pregnant women with gestational diabetes mellitus: an integrative review
Author(s) -
Ribanna Aparecida Marques Braga,
Maria Dinara de Araújo Nogueira,
Francisca Isabelle da Silva e Sousa,
Alexandre Danton Viana Pinheiro,
Maria Raquel da Silva Lima,
Antoniel Rodrigues Sousa,
Ana Clara Vital Batista,
Ana Lúcia Hoefel
Publication year - 2022
Publication title -
research, society and development
Language(s) - English
Resource type - Journals
ISSN - 2525-3409
DOI - 10.33448/rsd-v11i5.28199
Subject(s) - gestational diabetes , medicine , probiotic , diabetes mellitus , insulin resistance , carbohydrate metabolism , pregnancy , insulin , gestation , physiology , endocrinology , biology , genetics , bacteria
Aims: This literature review aims to investigate the effect of probiotic supplementation on glucose metabolism and inflammatory biomarkers in pregnant women with gestational diabetes mellitus. Methods: Data were collected using the National Library of Medicine (Medline), Latin American & Caribbean Health Sciences Literature (Lilacs), Virtual Health Library (BVS) and Scientific Electronic Library Online (Scielo) databases. The following descriptors were used: “gestational diabetes”, “probiotic” and “inflammation”. Results: The main findings emphasized the improvement in fasting glucose and insulin resistance and a lesser impact on the improvement of inflammatory markers after probiotic supplementation in pregnant women diagnosed with gestational diabetes mellitus. Conclusions: The use of probiotics in pregnant women with gestational diabetes mellitus has shown positive actions to control glucose metabolism and proinflammatory factors, which may improve serum glucose levels, insulin sensitivity and inflammation.