Open AccessObesity as a risk factor for heart failure: overview of systematic reviews
Author(s) -
Cleyton Oliveira Bezerra,
Rafael Marinho de Lima Paiva,
Thamires Lucena da Silva,
Valquíria Aparecida dos Santos Ribeiro,
Cínthia Caldas Rios,
Thaís Teles de Souza,
Wálleri Christini Torelli Reis
Publication year - 2022
Publication title -
research, society and development
Language(s) - English
Resource type - Journals
ISSN - 2525-3409
DOI - 10.33448/rsd-v11i1.24380
Subject(s) - overweight , obesity , scopus , risk factor , medicine , systematic review , population , protective factor , impact factor , gerontology , medline , environmental health , biology , biochemistry
The overweight and population with obesity has an increased risk of mortality from HF. However, some studies point to the existence of an "obesity paradox" where there could be a protective effect on the relative risk of death by HF in these populations with high BMI. In this way, the present study aimed to investigate obesity as a risk factor for heart failure. For this, an overview of systematic reviews was performed by selecting articles from the following databases: "Pubmed", "Scopus" and "SciElo”. A total of 615 articles were found from this initial search, leaving 59 articles for full-text reading, of which 22 articles were included for data extraction using the predefined inclusion criteria. From these 22 studies 73% were meta-analysis and 64% of the studies are of high methodological quality according to AMSTAR-2. Overweight and obesity have demonstrated a close relationship with the onset and increase of mortality by HF, studies have even been found that point to a gene interference in this relationship. In studies reporting on the obesity paradox, the results pointed to a momentary protection from mortality risk.