Open AccessVitamin D in the prevention and treatment of periodontal diseases: an integrative review
Author(s) -
Marlon Mezadri Layber,
Alyne Barreto Mesquita de Goés,
Camila Vilar de Oliveira Villarim,
Diego Maia Diógenes Rabelo Caldas,
Irami Araújo-Neto,
Laura Cristina Costa e Silva,
Amália Cínthia Meneses Rêgo,
Irami AraújoFilho
Publication year - 2021
Publication title -
research, society and development
Language(s) - English
Resource type - Journals
ISSN - 2525-3409
DOI - 10.33448/rsd-v10i13.20738
Subject(s) - vitamin d and neurology , medicine , vitamin d deficiency , osteoporosis , rickets , periodontitis , vitamin , cholecalciferol , bone remodeling , dentistry , physiology , gastroenterology , endocrinology
Vitamin D is synthesized from 7-dehydrocholesterol during a photochemical reaction, under the effect of ultraviolet radiation on the skin, obtained from food. It is hydroxylated in the liver to 25-hydroxyvitamin D3 (25(OH)D3). It is an active metabolite, which maintains the balance of calcium and phosphorus concentration in the blood, in addition to helping bone remodeling. Vitamin D deficiency promotes rickets in children and osteoporosis in adults, with a risk of bone fracture. Vitamin D acts in the pathogenesis of periodontal diseases via immunomodulation, increases mineral density and reduces bone resorption, which is important in combating agents that cause periodontal diseases. Objectives: Evaluate the importance of vitamin D in the prevention and treatment of periodontal diseases. Methods: A search was carried out in the PubMed/Medline, Scopus, Scielo, Embase, Web of Science and Google Scholar databases on scientifically proven evidence on the subject. Results: The present review demonstrated the importance of vitamin D in the prevention and treatment of periodontitis and the consequences of its deficiency on the oral health of patients. Conclusion: Vitamin D plays an important role in oral homeostasis and vitamin deficiency results in periodontal disease.