Open AccessAntimicrobial Resistance and Virulence of Staphylococcus spp. in patients from oncologic and non oncologic hospitals of Recife City/PE
Author(s) -
Marcelle Aquino Rabelo,
Stephanie Targino da Silva,
Jussyêgles Niedja da Paz Pereira,
Natália Regina Souza da Silva,
Vítor Hugo de Arimatéa Rocha,
Paulo Sérgio Ramos de Araújo,
Alzira Maria Paiva de Almeida,
Nilma Cintra Leal,
Maria Amélia Vieira Maciel
Publication year - 2021
Publication title -
research, society and development
Language(s) - English
Resource type - Journals
ISSN - 2525-3409
DOI - 10.33448/rsd-v10i10.18951
Subject(s) - cefoxitin , virulence , microbiology and biotechnology , biology , vancomycin , antimicrobial , staphylococcus aureus , staphylococcus , sccmec , antibiotic resistance , gene , methicillin resistant staphylococcus aureus , antibiotics , medicine , bacteria , genetics
Staphylococcus spp. is one of the major infection-associated bacteria within health care, especially in intensive care units, and one of principal cause of complication in cancer patients. This study compared the antimicrobial susceptibility profile and frequency of resistance (mecA, blaZ, ermA and ermC) and virulence (icaA, icaD and hlg) genes in Staphylococcus spp. from patients of Oncology Hospital (OH) and University Hospital (UH). The type of the ccr complex was assessed by PCR among the mecA positive isolates from the UH. Higher percentage of susceptible isolates, except for oxacillin and cefoxitin was found among the UH isolates and 27,3% vancomycin-resistant isolates were identified through the screening spot; 41 isolates displayed the MLSBc phenotype and five the MSLBi phenotype, and one isolate from the OH displayed the constitutive phenotype ermC gene. The ccr types I and II were identified with a higher frequency of ccr type I. No statistically significant difference was found in the frequency of the genes between the two groups of patients or in the two hospitals. Regarding the virulence genes, there was statistically significant difference when comparing the two hospitals.