Open AccessThe excitotoxic impairment of brain in patients with discirculatory encephalopathyand therapeutic correction
Author(s) -
Л. А. Шевченко,
V.І. Bobrova,
Володимир Калашник
Publication year - 2018
Publication title -
shìdno-êvropejsʹkij nevrologìčnij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2663-8444
pISSN - 2411-5797
DOI - 10.33444/2411-5797.2017.3(15).22-26
Subject(s) - excitotoxicity , medicine , electroencephalography , therapeutic effect , neurophysiology , encephalopathy , normalization (sociology) , anesthesia , neuroscience , psychology , nmda receptor , psychiatry , receptor , sociology , anthropology
In view of the proved fact of influence of excitotoxicity on progressive course of dyscirculatory encephalopa- thy, clinical, neurophysiological investigation of the patients in dynamics of treatment with cytoflavin and cortexin. The positive clinical dynamics and partial normalization of electroencephalographic patterns were found out. Correlation analysis have proved ambiguous connection between clinical signs, focal changes in brain and therapeutic effectiveness. Results of investigation have proved the appropriateness of dyscirculatory encephalopathy therapy with cytoflavin and cortexin with the aim of inhibition of excitotoxicity. Multiplevalued connection between obtained parameters allow to assume the necessity of future investigations on this problem.