Sleep disorders in patients with multiple sclerosis

Studied sleep disorders (SD) in patients with multiple sclerosis (MS) using a Severity scale of insomnia (ІSІ) and Sleepiness Scale Epworth (ESS) in comparison with the control groups and in the aspect of comorbidity, as well as to determine the correlations between the SD and the degree of disability, the level of severity of fatigue, depression, pain, quality of life (QOL). The study involved 207 MS patients with different forms of cours and 109 people who constituted the control group. Evaluated the clinical and demographic characteristics of the patients with MS due to comorbidity, determines the level of disability (EDSS), severity of pain (VAS), the severity of fatigue (FSS), depression (BDI-II), indicators of QOL (SF-36). Single or multiple co-morbidities found in 102 (49.3%) patients with MS, there was no co-morbidities in 105 (50.7%) patients with MS. It was found that more often among the SD in the study group of patients with MS observed insomnia (54.1%). It led to a decrease in the total duration of a night's sleep, as well as mainly predispose hypersomnia (43.0%). Also found that patients with MS I and II groups SD were significantly more likely than the control groups. It is shown that in patients with MS II group have a more severe manifestations of insomnia and daytime sleepiness (DS), which is associated with the presence of comorbid disease. According to the correlation analysis shows that the degree of the SD in patients with MS is closely correlated with the level of fatigue were also observed close correlation between insomnia and DS.