Quality of life in patients with multiple sclerosis comorbidity aspect with SF-36

We studied the quality of life (QoL) in patients with multiple sclerosis (MS) with the SF-36 compared to the control groups and in terms of comorbidity, as well as to determine the correlation between QoL and the degree of disability, the level of severity of fatigue, depression, pain, disorders of cognitive functions. The study involved 205 MS patients with different forms of course and 157 people made up the control group. Evaluated the clinical and demographic characteristics of the patients with MS due to comorbidity, determines the level of disability (EDSS), severity of pain (VAS), the severity of fatigue (FSS), depression (BDI-II), cognitive impairment (MMSE), quality of life ( SF -36 One or more concomitant disease was detected in 102 (49.3%) patients with MS, there was no co-morbidities in 105 (50.7%) patients with MS. It has been found that in patients with MS I and II groups QoL were significantly lower compared with controls both the individual scales, and by generalized indicators. Also found that during the correlation analysis between QoL and data EDSS, FSS, BDI-II, VAS and MMSE in patients with MS I and II the closest correlations were observed between the indices of quality of life and EDSS, and the least close - between QoL and MMSE. The most informative in establishing correlations between QoL and data EDSS, FSS, BDI-II, VAS and MMSE in patients with MS I and II according to our information was the scale of VT and generalized indicators MH and PH, and the least informative - the scale of GH. Also, it was found that the maximum reduction of generalized QoL in patients with MS group II (relative to the average for the group II) was associated with policomorbidity.