How reduce the risk of stroke after transient ischemic attack?

Microinfarction brain - small ischemic hearth to 5 mm in diameter typical for incomplete infarction (reduced number of neurons, axons, gliosis) and can be localized in both the cortex and subcortical structures. Micro- infarction may be associated with arteriolosklerozom, atherosclerosis large brain arteries, mikroembolii. The defeat of major cerebral vessels, which is the main cause of atherosclerosis, leads to larger (regional) cortical or subcortical infarcts and more often the cause of strokes. Recent studies demonstrated the development of severe endothelial dysfunction and platelet activation during the first week of ischemic stroke . Endothelial dysfunction was observed in all patients with stroke and was associated with progression of the clinical severity of stroke. Vascular instability and pro-coagulating activity continued in the first days after acute stroke and patients with increased risk of recurrent vascular events during the 1st week. It is important for patients with acute ischemic stroke, which brought severe endothelial dysfunction within the first 24 hours of hospitalization, and which progressively increases during the 1st week of hospitalization, despite a possible general trend of improvement of the clinical picture, can recommend at this time drugs that affect this negative process.