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Age and Gender- Based Antibiotic Susceptibility Patterns of Staphylococcus aureus among HIV Patients in Some Selected Hospitals in Anambra Central, Nigeria
Author(s) -
Josephine C. Anucha,
Ugonna C. Morikwe,
Moses Nkechukwu Ikegbunam,
Chinelo K. Ezejiegu,
M. C. Ugwu
Publication year - 2021
Publication title -
genetics and molecular medicine
Language(s) - English
Resource type - Journals
ISSN - 2689-1077
DOI - 10.33425/2689-1077.1011
Subject(s) - staphylococcus aureus , ofloxacin , tetracycline , erythromycin , gentamicin , medicine , cefuroxime , vancomycin , microbiology and biotechnology , antibiotic resistance , antibiotics , veterinary medicine , biology , ciprofloxacin , bacteria , genetics
Background: Emergence of resistant S. aureus strains is of great public health concern especially among the immune-compromised subjects. Method: A total of 236 mid-stream urine samples were obtained from the HAART departments of the selected hospitals in Anambra central. The isolates were identified using cultural and biochemical characterization. Their antibiotic susceptibility patterns were evaluated using disk-diffusion method. Results: Sixty-two (62) Staphylococcus aurues isolates were recovered from the 236 clinical samples. The S. aureus isolates showed 38.7% resistance to Vancomycin, 41.93% resistance to gentamicin, 33.8% resistance to ofloxacin, 48.39% resistance to tetracycline, 64.52% resistance to erythromycin and 100% resistance to Amoxicillinclavulanic acid and Cefuroxime. Twenty-four isolates were Vancomycin Resistant Staphylococus aureus (VRSA). Conclusion: The S.aureus isolates were multidrug resistant.

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