Open AccessCase Report: Preliminary Study on Expression of Oxidative Distress in Vaccinated Patients with Anti Sars Cov-2 Vaccine Bnt162b
Author(s) -
Antonella Maria Ilaria Cicale,
Salvatore Del Prete,
Antonio Del Prete
Publication year - 2021
Publication title -
journal of medical-clinical research and reviews
Language(s) - English
Resource type - Journals
ISSN - 2639-944X
DOI - 10.33425/2639-944x.1241
Subject(s) - cytokine storm , medicine , population , immunology , distress , covid-19 , immune system , oxidative phosphorylation , oxidative stress , virology , biology , environmental health , disease , clinical psychology , infectious disease (medical specialty) , biochemistry
Background: The study aims to investigate oxidative distress in patients vaccinated for Sars COV-2 by comparing them to patients infected with the virus. Case Presentation: The tests carried out on a small population of the female gender showed that the vaccine essentially does not create any oxidative distress unlike Sars COV-2 which instead generates an oxidative storm which, as per literature data, precedes the well-known cytokine storm. We assume that this is due to the different response induced by the vaccine which selectively stimulates lymphocytes without therefore stimulating the activity of macrophages which is instead activated by COVID-19. Conclusion: This study aims to be the starting point for a larger population study that correlates oxidative mechanisms with the vaccine-induced immune response.