Open AccessAntibody Response of Covishield Vaccine among Health Care Workers at Rajshahi Medical College Hospital- A Cross-Sectional Study
Author(s) -
Md. Azizul Haque,
Mohammad Hasan Tarik,
Ruhul Amin,
Md. Jahedul Islam,
Md Ariful Hasan,
Md Fazlul Kabir Bhuiyan
Publication year - 2022
Publication title -
taj
Language(s) - English
Resource type - Journals
eISSN - 2408-8854
pISSN - 1019-8555
DOI - 10.3329/taj.v34i2.58549
Subject(s) - medicine , vaccination , cross sectional study , health care , pandemic , antibody , antibody response , obesity , immunology , covid-19 , disease , infectious disease (medical specialty) , pathology , economics , economic growth
Background: Nationwide vaccination against SARS CoV-2 is the hope for stopping the pandemic and death from COVID-19. Till today several vaccines have been developed. In Bangladesh, the Covishield vaccine was the first coronavirus vaccine that was administered to health care workers on a priority basis. To assess antibody response in our community, evaluation of response in this group was necessary.Objectives: Our main aim of this study was to evaluate antibody response to SARS CoV-2 after vaccination with the Covishield vaccine in health care workers.Patients and Methods: It was a cross-sectional type study. Eighty-seven purposively collected health care workers were included in the study. Demographic profile, Co-morbidities, and other variables were recorded in a questionnaire. Blood samples were collected to assess SARS CoV-2 specific antibody.Results: Mean age in our study was 41.29±7.87 years. Most of them were between 35 to 44 years of age. Male: Female ratio was 3.35:1. Obesity (BMI>25) was present in 25.9% of individuals, hypertension in 33.3%, and DM in 14.9% of individuals. Overall 82.8% were vaccinated with the Covishield vaccine, and the remaining were not vaccinated. 96.6% were found to be antibody positive. All individuals (100%) who were either had a history of COVID-19 or received at least one shot of the Covishield vaccine were found antibody positive.Conclusion: Covishield vaccine was found to be highly effective in producing antibody response among healthcare workers.TAJ 2021; 34: No-2: 01-08