Open AccessSystemic Mastocytosis With Features of Chronic Liver Disease, Proptosis and Itchy Hyper-Pigmented Skin Lesion
Author(s) -
Md Benzamin,
Rafiqul Islam,
Mukesh Khadga,
Fatima Begum,
Wahiduzzaman Mazumder,
Shashi Bhushan Thakur,
Mizanul Hasan,
Asm Bazlul Karim
Publication year - 2020
Publication title -
kyamc journal
Language(s) - English
Resource type - Journals
eISSN - 2308-2860
pISSN - 2308-2720
DOI - 10.3329/kyamcj.v11i1.47152
Subject(s) - medicine , systemic mastocytosis , pathology , cutaneous mastocytosis , lesion , disease , dermatology , infiltration (hvac) , mast cell , bone marrow , cd34 , spleen , skin lesion , immunology , stem cell , physics , genetics , biology , thermodynamics
Mastocytosisis a rare disorder of functionally defective mast cells. Infiltration of this functionally defective mast cells and CD34+ mast cell precursors in various organ leads to clinical manifestation. Skin is the most common affected organ. In systemic mastocytosis along with skin, internal organs such as the liver, spleen, bone marrow, small intestines and eye also involve. Diagnosis is done on the basis of WHO diagnostic criteria. Here we presenting this rare entity presented to us with features of chronic liver disease, proptosis and itchy hyperpigmented skin lesion diagnosed as systemic mastocytosis.
KYAMC Journal Vol. 11, No.-1, April 2020, Page 50-53