Open AccessFVC, FEV1 and FEV1/FVC% in patients with Major Depressive Disorder
Author(s) -
Khandaker Nadia Afreen,
Sultana Ferdousi
Publication year - 2016
Publication title -
journal of bangladesh society of physiologist
Language(s) - English
Resource type - Journals
eISSN - 2219-7508
pISSN - 1995-1213
DOI - 10.3329/jbsp.v11i2.30652
Subject(s) - medicine , spirometer , depression (economics) , major depressive disorder , pulmonary function testing , vital capacity , physical therapy , spirometry , lung function , asthma , lung , exhaled nitric oxide , amygdala , diffusing capacity , economics , macroeconomics
Background: Major Depressive Disorder (MDD) is associated with depressed lung function.\udObjectives: To observe FVC, FEV1 and FEV1/FVC% in Major Depressive Disorder patients.\udMethods: This prospective study was carried out in the Department of Physiology, Bangabandhu\udSheikh Mujib Medical University (BSMMU) in 2014on 60 newly diagnosed female MDD patients\udaged 20 to 50 years. They were enrolled from the Department of Psychiatry of BSMMU. Age, BMI,\udsocioeconomic status and occupation matched 30 apparently healthy females were controls.FVC,\udFEV1 and FEV1/FVC% were assessed by a portable digital spirometer. For statistical analysis,\udIndependent sample ‘t’ test was done. Results: FVC, FEV1, FEV1/FVC% were significantly lower\ud(p<0.001) in all MDD patients than those of control. More over, 54(90%) MDD patients had abnormal\udpulmonary function test. Among them,5(9.25%) had obstructive,32(59.25%) had restrictive and\ud17(31.48%) had both restrictive and obstructive disorder. Conclusion: From this study it may be\udconcluded that significant depression of lung function may be associated with MDD, characterized\udby restrictive, obstructive and mixed type disorders.\u