Open AccessGonadoblastoma: Primary Amenorrhoea with Gonadal Dysgenesis
Author(s) -
Hamida Begum,
Sabera Khaton,
Sultana Jahan
Publication year - 1970
Publication title -
journal of bangladesh college of physicians and surgeons/journal of bangladesh college of physicians and surgeons
Language(s) - English
Resource type - Journals
eISSN - 2309-6365
pISSN - 1015-0870
DOI - 10.3329/jbcps.v26i2.4188
Subject(s) - gonadoblastoma , medicine , laparotomy , menstruation , gynecology , histopathology , uterus , girl , surgery , karyotype , pathology , chromosome , psychology , developmental psychology , biochemistry , chemistry , gene
A seventeen year old unmarried girl presented with no development of breasts and non establishment of menstruation till then. She was with average height & weight, chromosome analysis was 46XY (Swyer Syndrome). Laparoscopy followed by laparotomy showed irregular surfaced gonads with rudimentary uterus. Gonadectomy done & histopathology revealed features of gonadoblastoma. She had under gone 6 cycles of combination chemotherapy and hormone replacement therapy and showed excellent response. DOI: 10.3329/jbcps.v26i2.4188 J Bangladesh Coll Phys Surg 2008; 26: 97-99