Open AccessAssociation of serum zinc and vitamin E levels with Acne vulgarisin Bangladeshi acne patients
Author(s) -
Tania Sultana,
Aklima Akter,
Fatima Zohra,
Quddusur Rahman,
Yearul Kabir
Publication year - 2021
Publication title -
journal of bangladesh academy of sciences
Language(s) - English
Resource type - Journals
eISSN - 2224-7270
pISSN - 0378-8121
DOI - 10.3329/jbas.v45i1.54259
Subject(s) - acne , medicine , zinc , vitamin , vitamin d and neurology , vitamin e , endocrinology , antioxidant , dermatology , chemistry , biochemistry , organic chemistry
The serum level of zinc and vitamin E were measured to understand the association of various nutrients on acne pathogenesis. Both zinc and vitamin E are antioxidants used as a supplement in acne treatment. However, their effect and status in acne patients are not fully understood. This study included 48 acne patients and 48 sex- and age-matched healthy controls. The zinc and vitamin E concentration was measured in the serum by flame atomic absorption spectroscopy (AAS) and HPLC methods. Compared to the healthy control, a significant deficiency of serum vitamin E level in acne patients (p<0.001) was found, although the patients were not deficient in serum zinc level (p=0.22). In addition, female acne patients had a slightly lower zinc level than male patients (p=0.06). The low serum vitamin E level suggests that supplementation of vitamin E might be helpful in acne treatment. However, further studies are required to understand the dose and mechanism of vitamin E supplements in acne treatment.
J. Bangladesh Acad. Sci. 45(1); 49-58: June 2021