Open AccessCu(II), Zn(II), Cd(II) and Hg(II) Complexes of Pantroprazole (PPZH): Synthesis and Characterization
Author(s) -
Salma Begum,
Humaira Yeasmin,
Aasiya Shaikh,
Pradip K. Bakshi
Publication year - 2018
Publication title -
the dhaka university journal of science
Language(s) - English
Resource type - Journals
eISSN - 2408-8528
pISSN - 1022-2502
DOI - 10.3329/dujs.v66i2.54561
Subject(s) - chemistry , denticity , thermogravimetric analysis , metal , ligand (biochemistry) , divalent , metal ions in aqueous solution , zinc , inorganic chemistry , crystallography , stereochemistry , medicinal chemistry , organic chemistry , biochemistry , receptor
Several metal complexes of pantoprazole, [Cu(PPZ)(H2O)Cl], [Zn(PPZ)2], [Cd(PPZ)2].1.5H2O and [Hg(PPZ)(H2O)Cl] have been synthesized and characterized. Elemental analysis, IR, UV-Visible spectral analysis, magnetic measurement, thermogravimetric analysis, differential scanning calorimetric and cyclic voltammetric techniques were used for their characterization. The lipophilic weak base pantoprazole (PPZ) act as a potential bidentate ligand forming coordination complexes with divalent metal ions through anionic imidazolyl N- and O atom of sulfinyl >S=O group. All complexes possess tetrahedral geometry.
Dhaka Univ. J. Sci. 66(2): 151-156, 2018 (July)