Isolation and Characterization of Two Cucurbitane Type Triterpenoid Glycocide from 1-Butanol Soluble Part of Momordica charantia Fruit Pulp Juice | Zendy

M Shakhawoat Hossain | Zendy; Md. Kamrul Hasan | Zendy; Mohammad Shoeb | Zendy; MIR Mamun | Zendy; Nilufar Nahar | Zendy; M Mosihuzzaman | Zendy

Open Access

Isolation and Characterization of Two Cucurbitane Type Triterpenoid Glycocide from 1-Butanol Soluble Part of Momordica charantia Fruit Pulp Juice

Author(s) -

M Shakhawoat Hossain,

Md. Kamrul Hasan,

Mohammad Shoeb,

MIR Mamun,

Nilufar Nahar,

M Mosihuzzaman

Publication year - 2018

Publication title -

dhaka university journal of science

Language(s) - English

Resource type - Journals

eISSN - 2408-8528

pISSN - 1022-2502

DOI - 10.3329/dujs.v66i2.54560

Subject(s) - momordica , triterpene , chemistry , saponin , glycoside , dept , butanol , column chromatography , pulp (tooth) , cucurbitaceae , chromatography , thin layer chromatography , traditional medicine , organic chemistry , botany , stereochemistry , biology , ethanol , medicine , alternative medicine , pathology

Momordica charantia is a member of the Cucurbitaceae family having diverse biological activities. Two cucurbitane type triterpene glycoside have been isolated from 1-butanol soluble part of clear juice of M. charantia fruit pulp through column chromatography and HPLC. The isolated compounds were characterized as compound MC1 (3β, 7-O-β-glucopyranosyl-25-methoxy cucurbita –5-en-19-al) and compound MC2 (5β, 19-epoxy- 3- O-glucopyranosyl-25 methoxy cucurbita-6, 23-dien) with the help of UV Spectroscopy, Thin Layer Chromatography, IR Spectroscopy, 1H, 13C and dept-135 NMR. The proposed structures of the compounds were further confirmed by comparing the 13C-NMR values of the compounds with previous reported data. Dhaka Univ. J. Sci. 66(2): 145-149, 2018 (July)

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