Open AccessIsolation and Characterization of Two Cucurbitane Type Triterpenoid Glycocide from 1-Butanol Soluble Part of Momordica charantia Fruit Pulp Juice
Author(s) -
Muhammad Sajjad Hossain,
Md. Kamrul Hasan,
Mohammad Shoeb,
M. I. R. Mamun,
Nilufar Nahar,
M Mosihuzzaman
Publication year - 2018
Publication title -
the dhaka university journal of science
Language(s) - English
Resource type - Journals
eISSN - 2408-8528
pISSN - 1022-2502
DOI - 10.3329/dujs.v66i2.54560
Subject(s) - momordica , triterpene , chemistry , saponin , glycoside , dept , butanol , column chromatography , pulp (tooth) , cucurbitaceae , chromatography , thin layer chromatography , traditional medicine , organic chemistry , botany , stereochemistry , biology , ethanol , medicine , alternative medicine , pathology
Momordica charantia is a member of the Cucurbitaceae family having diverse biological activities. Two cucurbitane type triterpene glycoside have been isolated from 1-butanol soluble part of clear juice of M. charantia fruit pulp through column chromatography and HPLC. The isolated compounds were characterized as compound MC1 (3β, 7-O-β-glucopyranosyl-25-methoxy cucurbita –5-en-19-al) and compound MC2 (5β, 19-epoxy- 3- O-glucopyranosyl-25 methoxy cucurbita-6, 23-dien) with the help of UV Spectroscopy, Thin Layer Chromatography, IR Spectroscopy, 1H, 13C and dept-135 NMR. The proposed structures of the compounds were further confirmed by comparing the 13C-NMR values of the compounds with previous reported data.
Dhaka Univ. J. Sci. 66(2): 145-149, 2018 (July)