Open AccessBiological Screening of Zizyphus rugosa and Zizyphus oenoplia extractives
Author(s) -
Mohammad Shoeb,
M. I. R. Mamun,
Nilufar Nahar,
M. Mosihuzzaman
Publication year - 1970
Publication title -
the dhaka university journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 1816-1839
pISSN - 1816-1820
DOI - 10.3329/dujps.v4i2.216
Subject(s) - antibacterial activity , traditional medicine , bark (sound) , chemistry , lupeol , enterobacter aerogenes , candida rugosa , rugosa , ethyl acetate , friedelin , betulinic acid , chloroform , bacteria , microbiology and biotechnology , biology , botany , stereochemistry , biochemistry , organic chemistry , escherichia coli , medicine , enzyme , ecology , genetics , triterpenoid , gene , lipase
Different extracts of the leaves and barks of Zizyphus rugosa and Zizyphus oenoplia were studied for their antibacterial, antifungal, and b-glucuronidase inhibitory activities. The methanol extract of Z. rugosa bark showed significant antibacterial activity against Streptococcus pyogens, Staphylococcus aureus and Pseudomonas aerogenes whereas the methanol extract of leaves demonstrated moderate activity against Salmonella typhi. The chloroform and methanol extracts of Z. oenoplia showed good activity against a few bacteria strains. The chloroform extracts of the barks and leaves of Z. rugosaalso showed antifungal activity. The methanol and ethyl acetate extracts of the bark of Z. rugosa revealed significant b-glucuronidase inhibitory activity. Lupeol, betuline, betulinaldehyde and betulinic acid, isolated from Z. rugosa, also showed good activity against a few bacteria.
Key words: Zizyphus rugosa, Zizyphus oenoplia, Antibacterial, Antifungal, b-glucuronidase inhibition
Dhaka Univ. J. Pharm. Sci. Vol.4(2) 2005
The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website