Open AccessIn vitro Studies on Toxicological Property of the Root and Stem Bark Extracts of Oroxylum indicum
Author(s) -
Nargis Sultana Chowdhury,
Rezaul Karim,
Sohel Rana
Publication year - 1970
Publication title -
the dhaka university journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
eISSN - 1816-1839
pISSN - 1816-1820
DOI - 10.3329/dujps.v4i1.199
Subject(s) - brine shrimp , traditional medicine , bioassay , ethyl acetate , lethality , chemistry , biology , toxicology , medicine , biochemistry , genetics
This research work was carried out to investigate the toxicological activities of the medicinal plant Oroxylum indicum using Brine Shrimp Lethality Bioassay. It was found that the root and stem extracts of the plant contained some constituents that were toxic for the brine shrimp nauplii. The ether and alcohol extracts may have cytotoxic properties as well as other pharmacological activities but the ethyl acetate extract was not so active. The results are discussed with reference to the indication of using the plant extracts as an anti-mutagenic agent and appeared to be well-supported by their chemical constituents.
Key words: Oroxylum indicum, Toxicological activity, Brine shrimp lethality
Dhaka Univ. J. Pharm. Sci. Vol.4(1) 2005
The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website