Open AccessHaemoglobin D Trait-An Uncommon Haemoglobinopathy in Chattogram: A Case Report
Author(s) -
Razia Sultana,
Tani Gosh
Publication year - 2021
Publication title -
chattagram maa-o-shishu hospital medical college journal
Language(s) - English
Resource type - Journals
eISSN - 2306-4919
pISSN - 2305-7890
DOI - 10.3329/cmoshmcj.v20i1.53594
Subject(s) - sickle cell trait , medicine , loss of heterozygosity , trait , girl , compound heterozygosity , sister , family studies , pregnancy , pediatrics , disease , genetics , biology , phenotype , allele , sociology , computer science , anthropology , gene , programming language
This case presents haemoglobin D Trait (Hb-D) which is a rare disease in Bangladesh. It is a heterozygous state for haemoglobin D who came to Laboratory Medicine Department of Chattogram Maa Shishu-O-General Hospital (CMSOGH) for heamoglobin electrophoresis. Our patient was 9 years old girl from Noakhali, Bangladesh. She was clinically silent with no splenomegaly. Her peripheral blood film was microcytic hypochromic anaemia and Capillary Electrophoresis (CE) of Hb revealed Hb D Trait. On family screening her father was Hb E trait, mother was Hb D trait and younger sister turned out normal Hb study. Compound heterozygosity for haemoglobin D and haemoglobin E may be present in subsequent pregnancy of her mother.
Chatt Maa Shi Hosp Med Coll J; Vol.20 (1); January 2021; Page 81-83