Open AccessBiomarkers for Chronic Neuropathic Pain and Their Potential Application in Spinal Cord Stimulation (SCS) Therapy
Author(s) -
Miliva Mozaffor,
Abu Sadat Mohammad Nurunnabi,
Moshiur Rahman Khasru,
Md Joynul Islam
Publication year - 2022
Publication title -
community based medical journal
Language(s) - English
Resource type - Journals
eISSN - 2408-848X
pISSN - 2226-9290
DOI - 10.3329/cbmj.v10i2.59179
Subject(s) - neuropathic pain , medicine , neuromodulation , chronic pain , spinal cord stimulation , neurostimulation , spinal cord , anesthesia , physical therapy , physical medicine and rehabilitation , stimulation , psychiatry
Chronic neuropathic pain disorders represent a common long-term disability globally. Its treatment has limited success because of its poorly understood mechanisms. Moreover, the effectiveness of neuropathic pain management regimens and procedures have been difficult to determine to date, due to the subjectivity related to pain perception, and a lack of standardized assessment of neuropathic pain. However, one of the most effective and popular management strategies of chronic neuropathic pain in recent times is spinal cord stimulation (SCS), a form of neuromodulation. This review aims to understand which substances inside the human body increase and decrease with increasing neuropathic pain. Through identifying those biomarkers and finding correlations between neuropathic pain and those components, we would like to apply our knowledge to develop a biomarker profile which will ultimately help to see prognosis or predict success of spinal cord stimulation therapy in patients suffering from chronic neuropathic pain.
CBMJ 2021 January: vol. 10 no. 02 P: 118-122