Open Access
Association of vitamin D and insulin resistance among the adults with newly detected prediabetes attending in a tertiary care hospital of Bangladesh
Author(s) -
Md Maruf Haque Khan,
M Fariduddin,
Shahjada Selim,
Muhammad Mehboob Alam,
Md Shahed Morshed,
Md Habibul Ghani
Publication year - 2022
Publication title -
bangabandhu sheikh mujib medical university journal
Language(s) - English
Resource type - Journals
eISSN - 2224-7750
pISSN - 2074-2908
DOI - 10.3329/bsmmuj.v14i4.56617
Subject(s) - prediabetes , medicine , insulin resistance , diabetes mellitus , vitamin d deficiency , vitamin d and neurology , population , cross sectional study , insulin , endocrinology , type 2 diabetes , environmental health , pathology
Several studies have found an inverse association between vitamin D level and insulin resistance (IR) causing prediabetes and diabetes. So the current study was done to find out the association between serum vitamin D level and IR among adults with prediabetes. This cross-sectional study was carried out in 140 newly detected adults with prediabetes according to ADA 2018 criteria. The 25(OH) D cutoffs to define deficiency and insufficiency were used according to Endocrine Society (USA) criteria, measurement of vitamin D & insulin (fasting) was done by chemiluminescent microparticle immunoassay (CMIA). Data were analyzed using SPSS (version 22.0) and presented as table and figure. P-value ≤0.05 was considered significant. In this study, most of the population was 30 years and above (73%). The Male-female ratio was 1:7, the majority of participants came from urban areas (81%) and it was observed that there was an increasing trend of insulin resistance across increasing severity of vitamin D deficiency though it was not statistically significant (p= 0.74). In conclusion, vitamin-D deficiency/insuffi- ciency is common among individuals with prediabetes in our country, but there were no associ- ation had been found between vitamin D and insulin resistance in individuals with prediabetesBSMMU J 2021; 14(4): 157-162