Open AccessCorrelation of CA-125 with different stages of endometriosis
Author(s) -
Runa Laila,
Noorzahan Begum,
Shayela Shamim,
Mohammed Mainul Hoque
Publication year - 2018
Publication title -
bangabandhu sheikh mujib medical university journal
Language(s) - English
Resource type - Journals
eISSN - 2224-7750
pISSN - 2074-2908
DOI - 10.3329/bsmmuj.v11i1.35807
Subject(s) - endometriosis , medicine , stage (stratigraphy) , gastroenterology , cancer antigen , positive correlation , correlation , cutoff , gynecology , cancer , paleontology , physics , geometry , mathematics , quantum mechanics , biology
This study was conducted to evaluate the association of serum cancer antigen (CA-125) level with the severity of pelvic endometriosis. Seventy diagnosed cases of pelvic endometriosis were included in this study. The CA-125 level was estimated in all these patients, cutoff value of the serum CA-125 level was considered 35.0 U/mL. The correlations between serum CA-125 and different stages of endometriosis were evaluated by linear regression analysis. In Stage I of endometriosis, the mean serum CA-125 level was 21.8 ± 15.1 U/mL, in Stage II 26.0 ± 17.3 U/mL, in Stage III 83.2 ± 48.9 U/mL and in Stage IV 117.0 ± 41.6 U/mL. A significant positive correlation (r=0.729; p=0.001) was found between the serum CA-125 and different stages of endometriosis.