Open AccessOne step cyclocondensation of (thio) barbituric acid with chalcones in glacial acetic acid and phosphorous pentoxide, Part-II
Author(s) -
Khaleda Akhter,
ME Halim,
S.M. Zabed Ahmed,
Prabir Sarkar,
Farjana Akter,
Khurshid Jahan,
Ukr Romman,
Monzur Morshed Ahmed
Publication year - 2017
Publication title -
bangladesh journal of scientific and industrial research
Language(s) - English
Resource type - Journals
eISSN - 2224-7157
pISSN - 0304-9809
DOI - 10.3329/bjsir.v52i2.32921
Subject(s) - barbituric acid , acetic acid , chemistry , pentoxide , thiobarbituric acid , thio , phosphorus pentoxide , elemental analysis , proton nmr , carbon 13 nmr , organic chemistry , medicinal chemistry , nuclear chemistry , antioxidant , lipid peroxidation , vanadium
A number of new 5, 7-diaryl-1,5-dihydro (or 1, 2, 3, 5-tetrahydro)- pyrano [2, 3-d] pyrimidin-2, 4-diones (or 2-thioxo-4-ones) (3a-g) have been synthesized in one-step by cyclocondensation of barbituric acid or thiobarbituric acid (1) with arylideneacetophenones (2a-d), in glacial acetic acid in the presence of phosphorous pentoxide. The structures of the compounds 3a-g have been determined by UV, IR, 1H NMR, 13C NMR, mass spectral data and elemental analyses. The compounds 3a-g do not seem to be available in the literature.Bangladesh J. Sci. Ind. Res. 52(2), 115-124, 2017