Open AccessEffect of ethanol extract of leaves of <i>Azadirachta indica</i> on palmar arsenical keratosis: A single-blind trial
Author(s) -
Jannatul Ferdoush,
Mir Misbahuddin
Publication year - 2014
Publication title -
bangladesh journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.385
H-Index - 23
eISSN - 1991-0088
pISSN - 1991-007X
DOI - 10.3329/bjp.v9i3.19488
Subject(s) - azadirachta , salicylic acid , ethanol , traditional medicine , medicine , chemistry , biochemistry
The effectiveness of topical application of ethanol extract of Azadirachta indica (neem) daily for 12 weeks was examined in patient of palmar arsenical kera-tosis. The mean (± SD) score of size of nodules of patients (n=14) using sali-cylic acid alone before and after treatment were 14.6 ± 4.6 and 10.5 ± 4.5 respectively (28.1% improvement). The mean score of size of nodules of pati-ents (n=15) using salicylic acid plus A. indica (ethanol extract) before treatment was 14.7 ± 4.6 which was decreased to 3.1 ± 2.2 after treatment (79% improve-ment). The perception score of salicylic acid-treated group was 2.1 whereas it was increased to 4.7 in A. indica plus salicylic acid-treated group. Based on palmar nodular size and patients perception it can be concluded that topical use of ethanol extract of A. indica is effectively in palmar arsenical keratosis