In vitro antifungal, anti-oxidant and HPLC analysis of the extracts of Physalis philadelphica | Zendy

Wajid Khan | Zendy; Jehan Bakht | Zendy; Bilal Muhammad Khan | Zendy

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In vitro antifungal, anti-oxidant and HPLC analysis of the extracts of Physalis philadelphica

Author(s) -

Wajid Khan,

Jehan Bakht,

Bilal Muhammad Khan

Publication year - 2017

Publication title -

bangladesh journal of pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.385

H-Index - 23

eISSN - 1991-0088

pISSN - 1991-007X

DOI - 10.3329/bjp.v12i3.31965

Subject(s) - antifungal , physalis , in vitro , high performance liquid chromatography , chemistry , traditional medicine , anti oxidant , chromatography , biology , microbiology and biotechnology , biochemistry , antioxidant , medicine

The different parts of Physalis philadelphica were evaluated for the antifungal, anti-oxidant and HPLC assay. The methanol extract of leaf showed inhibitory activity against Pencillium digitatum (58% ZI), Aspergillus flavus (95% ZI) and Rhizopus oryzae (96% ZI) at a concentration of 400 ppm. Strong anti-oxidant activities were found in different parts of the plant. The effects of different extraction solvents on the anti-oxidant activity and antifungal activity of the medicinal extracts were observed. The methanol extract from the leaf, stem, fruit and water fractions from the calyx exhibited strong anti-oxidant activity of 94, 89, 88 and 93% respectively. The ethyl acetate extract was found as a best solvent for the recovery of gallic acid in HPLC assay. No correlation was observed between the gallic acid and anti-oxidant capacity of the extracts. Video Clip of Methodology : 11 min 13 sec: Full Screen Alternate

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