Open AccessAntibacterial activities, antioxidant contents and antioxidant properties of three traditional Chinese medicinal extracts
Author(s) -
Wenbin Li,
Hongyan Sun,
Jingran Zhou,
Yabiao Zhang,
Linjie Liu,
Ye Gao
Publication year - 2015
Publication title -
bangladesh journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.385
H-Index - 23
eISSN - 1991-0088
pISSN - 1991-007X
DOI - 10.3329/bjp.v10i1.21324
Subject(s) - scutellaria baicalensis , coptis chinensis , traditional medicine , chemistry , antioxidant , antibacterial activity , minimum inhibitory concentration , flavonoid , antimicrobial , biology , medicine , traditional chinese medicine , biochemistry , bacteria , organic chemistry , alternative medicine , pathology , genetics
The present study was carried out to identify antibacterial and antioxidant characteristics of traditional aqueous extracts derived from three traditional Chinese medicinal plants (Scutellaria baicalensis, Coptis chinensis and Sonchus oleraceus). It was indicated that the S. oleraceus showed the highest antibacterial efficacy, especially against Staphylococcus aureus. The minimum inhibitory concentration (MIC) of the S. oleraceus was 5.0 mg/mL what was in correlation with the high total phenolic and flavonoid contents and CUPRAC value, and MIC of both S. baicalensis and C. chinensis was 7.5 mg/mL. The rational pH of the working S. oleraceus was acidic, while the other two preferred to neutral or alkaline environment. The reasonable preservation temperature of S. baicalensis should not beyond 60°C, while the other two below 90°C. Meanwhile, S. baicalensis had significant antioxidant activity with the highest CUPRAC and ·OH scavenging activity. These results had provided useful information on further drug discovery