Open AccessFunctional Neuroimaging: Single Photon Emission Computed Tomography (SPECT) In Neurological Disorders
Author(s) -
Aminur Rahman,
Farhana Salam,
Rowshan Ara Begum,
Afroza Akhter,
Shahryar Nabi,
Md. Khalilur Rahman,
Md Tariqul Islam,
Zahed Ali,
Uttam Kumar Saha,
Firoz Ahmed Quraishi
Publication year - 2018
Publication title -
bangladesh journal of neuroscience
Language(s) - English
Resource type - Journals
eISSN - 2408-8382
pISSN - 1023-4853
DOI - 10.3329/bjn.v34i2.57554
Subject(s) - single photon emission computed tomography , neuroimaging , cerebral blood flow , emission computed tomography , functional imaging , medicine , magnetic resonance imaging , perfusion , cerebral perfusion pressure , neuroscience , positron emission tomography , perfusion scanning , spect imaging , radiology , nuclear medicine , functional neuroimaging , brain mapping , psychology , cardiology
A single photon emission computed tomography (SPECT) scan is a functional nuclear imaging technique performed to evaluate regional cerebral perfusion. Because cerebral blood flow is closely linked to neuronal activity, the activity distribution is presumed to reflect neuronal activity levels in several areas of the brain. Although structural magnetic resonance imaging (MRI) and computed tomography (CT) provide exquisite anatomical detail, SPECT provide complementary functional information. Frequently, brain pathology will manifest as functional changes before anatomical changes are detectable. SPECT has clinical value in the diagnosis, therapeutic management, and follow-up of patients. A general consideration of the clinical value of this technique is followed by relevant information on cerebral physiology and pathology for proper understanding of brain SPECT images. The diversity of central nervous system diseases and therefore the still incomplete knowledge of the mechanisms that underlie them have contributed to the success of brain perfusion SPECT as a research tool in neurosciences. Finally, stepby- step recommendations for interpreting and reporting brain perfusion SPECT images are provided to get the utmost clinical beneût from this technique.Bangladesh Journal of Neuroscience 2018; Vol. 34 (2): 96-105