Open AccessSignal Transduction Pathway in Chronic Leukemia
Author(s) -
Faris Q. Alenzi
Publication year - 2017
Publication title -
bangladesh journal of medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.255
H-Index - 10
eISSN - 2079-6854
pISSN - 2076-0299
DOI - 10.3329/bjms.v16i1.31127
Subject(s) - signal transduction , medicine , intracellular , gene , microbiology and biotechnology , cell , transduction (biophysics) , cancer research , biology , genetics , biochemistry
It is becoming progressively clearer that the three RAS genes, N-. H-and K-RAS, encode 21 kDa proteins which act as intracellular switches, playing important roles in the signal transduction pathway that control cell development and maturation. These three genes are profoundly homologous, yet more recent findings indicate they have important roles in the functions various cell types playing focal roles in numerous human infections. This article briefly reviews the regulation of RAs-dependent signaling mechanisms.Bangladesh Journal of Medical Science Vol.16(1) 2017 p.21-23