Open AccessQualitative evaluation of antibacterial and DNA binding activity of four local ethnomedicinal plants available in Barishal, Bangladesh
Author(s) -
Mahmudul Hassan Suhag,
Uzzal Hossain,
Sohel Ahmed,
Nazmul Kayes
Publication year - 2020
Publication title -
asian journal of medical and biological research
Language(s) - English
Resource type - Journals
eISSN - 2412-5571
pISSN - 2411-4472
DOI - 10.3329/ajmbr.v6i3.49796
Subject(s) - escherichia coli , antibacterial activity , traditional medicine , staphylococcus aureus , biology , dna , medicinal plants , aloe vera , bacteria , chemistry , microbiology and biotechnology , biochemistry , medicine , gene , genetics
Screening of antibacterial activities of plants due to secondary metabolites is an authentic basis to look for a new drug. As a result of increasing demand for traditional treatments, scientists have look forward to search the efficacy of these so called ethnomedicinal plants and have to exchange with pharmacologists. An initiative of this, the antibacterial activity of Ecliptaprostrata(L.)Mant.AzadirachtaindicaA. Juss., Aloe vera(L.)Burm.f. and Catharanthusroseus(L.) G. Don was studied against Escherichia coli and Staphylococcus aureus. Among four ethnomedicinal plants subjected to test antibacterial activities, Ecliptaprostratawas found to act against both strains of bacteria whereas Azadirachtaindicawas effective against Escherichia coli only. DNA binding affinity of these medicinal plants was also studied by viscometry. No affinity between each medicinal plant extracts and isolated human cheek cell’s DNA was observed.
Asian J. Med. Biol. Res. September 2020, 6(3): 475-481