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Influence of triclosan biocide on human health and environment and justification of the necessity to optimise regulatory measures for its use
Author(s) -
Г.М. Балан,
Serhii Kolesnyk,
P.G. Zhminko,
Nataliia Bubalo,
V.A. Babych
Publication year - 2019
Publication title -
ukraïnsʹkij žurnal sučasnih problem toksikologìï/ukraïnsʹkij žurnal sučasnih problem toksikologìï
Language(s) - English
Resource type - Journals
eISSN - 2663-9165
pISSN - 2663-4570
DOI - 10.33273/2663-4570-2019-86-2-22-28
Subject(s) - triclosan , biocide , endocrine disruptor , human health , cosmetics , risk analysis (engineering) , regulatory science , endocrine system , environmental health , biochemical engineering , business , medicine , biology , engineering , ecology , pathology , hormone
Objective is to summarise current literature data on the adverse effects of triclosan (TCS) biocide on human and animal health and potential risk for the development of endocrine-disruptor effects forjustification of the necessity to improve regulatory measures for its use in consumer products.Material and Methods. Analysis of literature data on the ways of influence of metabolic transformation in the body and toxicokinetics of TCS, its influence on human health and environment was performed. Targets and biomarkers of TCS exposure, its toxic properties and potential risk for the formation of endocrine-disruptor effects were described.Results. Necessity to optimise regulatory measures for the use of TCS in the personal hygienic means, general and curative beauty products, woven fabric for bedlinen and underwear, etc. has been justified.Key Words: triclosan biocide, toxic properties, endocrine-disruptor effects, regulatory measures.

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