Open AccessSolvent-free Synthesis, Characterization and Biological Activity of Transition Metal Complexes of Schiff Base Ligand Derived from 2-Amino Benzimidazole with 4, 4’Dibromobenzil
Publication year - 2021
Publication title -
letters in applied nanobioscience
Language(s) - English
Resource type - Journals
ISSN - 2284-6808
DOI - 10.33263/lianbs113.38343842
Subject(s) - schiff base , benzimidazole , chemistry , ligand (biochemistry) , transition metal , octahedral molecular geometry , metal , polymer chemistry , antibacterial activity , nuclear chemistry , combinatorial chemistry , organic chemistry , bacteria , biochemistry , catalysis , biology , receptor , genetics
Microwave-assisted synthesis and characterization of Schiff base ligand complexes of transition metals such as Mn(II), Fe(III), Co(II), Ni(II),Cu(II), Zn(II) Cd(II), and Ag(I) (using Schiff base) prepared by irradiation of 2-Amino benzimidazole with 4,4’dibromo benzil. The Synthesized transition metal complexes and Schiff base ligand have been representatively characterized by elemental analysis and spectral methods such as UV, IR, 1H-NMR, LC-MS, and Thermal analysis. The synthesized ligand and its complexes were also screened for their biological activities, such as antibacterial activity against bacterial species Staphylococcus aureus, Escherichia coli, and Salmonella Typhi. The result indicated that the complexes exhibited octahedral geometry.