Open AccessComputer-aided Identification of Synergetic Wound Healing Mechanisms Exhibited by Compounds in the Bio Synthesized Wound Dressing Material
Publication year - 2021
Publication title -
letters in applied nanobioscience
Language(s) - English
Resource type - Journals
ISSN - 2284-6808
DOI - 10.33263/lianbs104.28312842
Subject(s) - wound healing , chemistry , wound dressing , biomaterial , organic chemistry , materials science , surgery , medicine , composite material
A wound dressing material synthesized from the bio-composites of chicken fibrin, fish scale collagen impregnated with the spider web, and the ethanolic leaves extract of Mangifera indica (L.). The synthesized biomaterial was analyzed by GC-MS analysis. The present study involves identifying bioactive compounds that may heal wounds from the biosynthetic wound dressing material and the biological activities determined with the help of PASS software online prediction. PASS online software is used to explore the mechanism involved in healing wound compounds. Ten bioactive compounds identified as wound healing agents 2-methyl 4-Heptanol, 3-methoxy Hexane, Stigmasterol, Z-3,17-Octadecadien-1-ol acetate, 3-Chloro-5 Cholestene, 9,12,15 Octadecatrienoic acid 2,3 –Bis(acetyloxy) propyl ester(Z, Z, Z), Trans-Z-.alpha.-bisabolene epoxide, Beta carotene, Nopyl Acetate, 9,12 Octadecadienoic acid (Z, Z)phenylmethyl ester, and their bioactivities analyzed. Analyzed bio compounds found to exhibit wound healing mechanisms.