Open AccessSynthesis and Biological Evaluation Study of New Bis-imine Ligand and Metal Complexes
Publication year - 2020
Publication title -
letters in applied nanobioscience
Language(s) - English
Resource type - Journals
ISSN - 2284-6808
DOI - 10.33263/lianbs102.22072214
Subject(s) - imine , ligand (biochemistry) , metal , chemistry , schiff base , hydrazine (antidepressant) , combinatorial chemistry , polymer chemistry , organic chemistry , catalysis , receptor , biochemistry , chromatography
A new Schiff base bis-imine ligand was synthesized by the reaction of 1-(2-bromo, 5-methoxy benzylidene) hydrazine and 5-chlorosalicylaldehyde. This bis-imine ligand was used for the synthesis of metal complexes. The synthesized ligand and metal complexes were characterized by spectroscopic techniques. The metal complexes were formed in the ligand to metal ratio of 2:1. The synthesized metal complexes were screened for antimalarial, anti-tubercular, and antimicrobial activities.