Simple and Reliable Method for the Estimation of Albendazole in Antiparasitic Drug Formulations

From the literature survey, it is confirmed that there are only a few analytical methods for the determination of albendazole. The principle behind this investigation is to produce a simple, exact and quick method of titrimetry for the quantification of albendazole. Albendazole having an oral broad-spectrum biological activity present in pharmaceutical drugs is determined using a conventional and reliable iodometric method using chloramine-T as an oxidant. The method involves the oxidation of sulfur by chloramine-T in glacial acetic acid, followed by the iodometric determination of the unreacted chloramine-T.