
Protein structure from the essential amino acids to the 3D structure
Author(s) -
Diaa Atta,
Abeer E. Mahmoud,
Ahmed Fakhry
Publication year - 2019
Publication title -
biointerface research in applied chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.216
H-Index - 11
ISSN - 2069-5837
DOI - 10.33263/briac91.817824
Subject(s) - protein tertiary structure , protein structure prediction , protein structure , protein quaternary structure , protein secondary structure , computational biology , amino acid , beta sheet , polypeptide chain , chemistry , biology , computer science , biochemistry , protein subunit , gene
Protein structure is a hot topic, not only to the specialist, but with others like the physicists. So this review is targeting those who are not biologists and have to deal with the protein in their research. In this review we travel with the protein structures from the amino acids and its classifications, and how the polypeptide chain is formed from these building blocks up to the final 3D structure. We introduced the secondary structure species like helices with its different types and how it is formed; also the beta sheet formation and types are explained briefly. Finally the tertiary and quaternary structures are presented. The approaches of molecular modeling as well as other important computational methods present significant contribution to studying proteins.