Open AccessEpidemiological, clinical and virological aspects of hepatitis B, C and D coinfection in individuals infected with human immunodeficiency virus type-1
Author(s) -
Bogdan Ionescu,
Grigore Mihaiescu
Publication year - 2011
Publication title -
biointerface research in applied chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.216
H-Index - 11
ISSN - 2069-5837
DOI - 10.33263/briac14.145150
Subject(s) - coinfection , hepatitis c virus , medicine , transmission (telecommunications) , virology , cirrhosis , hepatitis c , hepatitis b , hepatitis b virus , liver disease , hepatitis , epidemiology , immunology , disease , human immunodeficiency virus (hiv) , virus , electrical engineering , engineering
After the introduction of the HAART therapy the spectrum of illnesses challenging HIVcare providers has changed significantly. At present, end stage liver disease and cirrhosiscaused by the coinfections with hepatitis C virus (HCV) and hepatitis B virus (HBV)cause more morbidity and mortality than any other conditions encountered in HIV infectedpatients. The number of people suffering from the coinfections with the hepatitis viruseshas been steadily increasing over the last years. The shared routes of transmission havelead to 10% of HIV positive people becoming infected with hepatitis B and 15% to30% with hepatitis C, resulting in over 4 milion HIV/HBV and respectively 10 milionHIV/HCV coinfected individuals around the world. The purpose of this paper is to reviewthe main sources of transmission of the coinfections and the differences in their progressas compared to mono-infections