Open AccessInvestigation of the Antioxidant and Antitumour Properties of Some Cyclobutane Ring Containing 2,5-Thiophene Diacyl Compounds
Publication year - 2021
Publication title -
biointerface research in applied chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.216
H-Index - 11
ISSN - 2069-5837
DOI - 10.33263/briac122.24502461
Subject(s) - thiophene , antioxidant , lipid peroxidation , chemistry , oxidative stress , vitamin c , in vitro , vitamin e , cyclobutane , biochemistry , ring (chemistry) , organic chemistry
In this research, the effect of thiophene derivatives on the (MDA) concentration which is an indicator of lipid peroxidation, antioxidant vitamins A, E and in vitro antioxidant activity and antitumor activity, were investigated in cell culture media. In the comparison done among groups, it was observed that MDA and vitamin A concentrations were statistically (P<0.05) changed. Looking at the measured parameters during the experiment, the number of live cells, the compounds is an effective antitumor activity in the L 1210 cell types. The oxidative stress parameters are used for all compounds.