Open AccessFlavonoid and Diterpenoid Components from Teucrium orientale subsp. orientale and their Radical Scavenging Activity
Author(s) -
Melika Alviri,
Mir Babak Bahadori,
S H Ranjbar Bahadori
Publication year - 2021
Publication title -
biointerface research in applied chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.216
H-Index - 11
ISSN - 2069-5837
DOI - 10.33263/briac121.682689
Subject(s) - teucrium , phytochemistry , chemistry , lamiaceae , terpenoid , dpph , column chromatography , quercetin , traditional medicine , luteolin , lupeol , flavonoid , chromatography , organic chemistry , antioxidant , botany , stereochemistry , biology , medicine
Being a member of the Lamiaceae family, Teucrium orientale (named Maryam Nokhodi in Iran) grows in Iran, Turkey, Iraq, Caucasus, Syria, Lebanon, Afghanistan, Pakistan, Turkmenistan, Central Asia, Europe, and North Africa. Among the pharmacological effects, Teucrium orientale is confirmed to have antidiabetic, antihemorrhoidal, antidysmenorrhea, antioxidant, antipyretic, antibacterial, anticandidal, and pesticide effects. The genus Teucrium comprises many bioactive compounds, including flavonoids, monoterpenes, sesquiterpenes, diterpenoids, phenolic acids, and fatty acid esters. In this work, in order to investigate the phytochemistry of Teucrium orientale, the aerial parts of the plant were extracted by maceration. The column chromatography technique was used to fractionate the acetonic extract. Purified compounds were obtained by smaller chromatography columns and techniques, including preparative thin layer chromatography, precipitation, and recrystallization. Chemical structures of compounds were identified by NMR and FT-IR spectroscopy and also elemental analysis. The compounds were elucidated as sclareol, quercetin, and luteolin. Furthermore, the antioxidant activity of the isolated compounds was evaluated.