Open AccessSolid-State Fermentation in Brewer’s Spent Grains by Fusarium fujikuroi for Gibberellic Acid Production
Publication year - 2021
Publication title -
biointerface research in applied chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.216
H-Index - 11
ISSN - 2069-5837
DOI - 10.33263/briac115.1304213052
Subject(s) - gibberellic acid , fermentation , gibberella fujikuroi , food science , solid state fermentation , water content , central composite design , moisture , chemistry , production (economics) , mathematics , microbiology and biotechnology , botany , gibberellin , biology , response surface methodology , engineering , germination , chromatography , organic chemistry , geotechnical engineering , macroeconomics , economics
The search for new production methodologies of gibberellic acid (GA3), such as solid-state fermentation (SSF), and the use of agro-industrial waste are important to lower production costs. Therefore, the aim of this study was GA3 production by Fusarium fujikuroi on SSF mode using brewer’s spent grains (BSG). BSG presents in its composition components that are known to be excellent inducers of metabolite production, showing, this way, its potential to be used as the substrate in biotechnological processes. Optimization of GA3 production was carried out using a 22 central composite design, considering the effects of moisture content, temperature, and fermentation time. The highest mycelial growth and GA3 production (0.82 g.Kg-1) was obtained in the condition of 80% moisture content, 28 °C in 96 hours of fermentation. These results suggest that the SSF using BSG as the medium for the growth of F. fujikuroi is a viable way to GA3 produce.