Open AccessA Possible Destruction of SARS-CoV-2 by a Cylindrical Probe Coated with the Graphene Oxide: A Thermal-based Model
Author(s) -
Tony Sumaryada,
Fiqhi Ramadhan
Publication year - 2021
Publication title -
biointerface research in applied chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.216
H-Index - 11
ISSN - 2069-5837
DOI - 10.33263/briac115.1270612716
Subject(s) - graphene , oxide , covid-19 , thermal , materials science , limit (mathematics) , adsorption , nanotechnology , chemistry , physics , virology , thermodynamics , mathematics , medicine , disease , pathology , biology , outbreak , infectious disease (medical specialty) , metallurgy , mathematical analysis
In this paper, the possible use of graphene oxide (GO) to destroy SARS-CoV-2 of COVID-19 is modeled. A molecular docking approach was first conducted to estimate the binding energy of GO with the spike glycoprotein of SARS-CoV-2 virus (SGCoV). A simple space-limited geometry model is used to set up the maximum limit of SARS-CoV-2 that can be absorbed on the GO surface. Using the GO surface as a hotbed for virus destruction and utilizing the unique properties of GO (the molecular weight, the area to mass ratio, and the specific heat), we build a thermal-based model to explore the possibility of destroying the adsorbed SARS-CoV-2 on the GO-coated cylindrical probe. A hypothetical design of a medical device that could benefit from this model is also proposed here.