Open AccessMolecular Docking Performance of Selective Organic Compounds with Target Protein
Publication year - 2021
Publication title -
biointerface research in applied chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.216
H-Index - 11
ISSN - 2069-5837
DOI - 10.33263/briac114.1241412424
Subject(s) - docking (animal) , chemistry , calmodulin , hydrogen bond , binding site , biochemistry , phenoxazine , receptor , protein–protein interaction , acetylcholinesterase , target protein , enzyme , pharmacology , biology , molecule , gene , medicine , nursing , organic chemistry , phenothiazine
In this article, the docking analysis has been carried out to know some selective compounds' interaction to bind with a targeted protein. There are three approaches have been analyzed here with three different kinds of protein as the target species. They are 2-aminobenzimidazole (2ABZ) with Acetylcholinesterase receptor (AChE), Phenoxazine (POZ) with Penicillin-binding proteins (PBPs) receptor, and Phenothiazines with Calcium/calmodulin-dependent protein kinase IV (CAMK IV) receptor. All three studies showed that the binding is perfect at the binding site and explained with hydrogen bonding interaction via donor-acceptor interactions.