Open AccessAnticancer Properties of some Novel 2-Hetaryl-3-(5-Arylfuran-2-yl)-Acrylonitriles
Publication year - 2020
Publication title -
biointerface research in applied chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.216
H-Index - 11
ISSN - 2069-5837
DOI - 10.33263/briac112.88448853
Subject(s) - elemental analysis , in vitro , chemistry , cancer cell lines , combinatorial chemistry , stereochemistry , cancer , organic chemistry , cancer cell , biochemistry , medicine
In our present work, we displayed an effective synthesis and anticancer activity assessment of some novel 2-hetaryl-3-(5-arylfuran-2-yl)-acrylonitriles. The structures of synthesized substances were determined by 1H NMR spectroscopy and elemental analysis. In vitro anticancer activity assessment on the full panel of about 60 human cancer cell lines showed that received compounds displayed a weak and moderate kind of activity.