Open AccessBiological and Electrochemical Studies of Macrocyclic Complexes of Iron and Cobalt
Author(s) -
Vivek Sharma,
Vinod Kumar Vashistha,
Dipak K. Das
Publication year - 2020
Publication title -
biointerface research in applied chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.216
H-Index - 11
ISSN - 2069-5837
DOI - 10.33263/briac111.73937399
Subject(s) - cyclic voltammetry , electrochemistry , chemistry , cobalt , octahedron , electron transfer , octahedral molecular geometry , metal , metal ions in aqueous solution , ion , macrocyclic ligand , crystallography , inorganic chemistry , stereochemistry , electrode , organic chemistry
In this work, we synthesized two tetraaza [N4] macrocyclic complexes of FeIII and CoII metal ions. The synthesized macrocyclic complexes were fully characterized by using various analytical techniques IR, UV-Vis, and MS. The spectral analysis indicated an octahedral geometry for both macrocyclic complexes. The electrochemical behavior was carried out using cyclic voltammetry on the Pt dish (0.031 cm2) electrode. The complexes were shown to have unusual oxidation states for the metal ions. The “heterogeneous electron transfer rate constant” (Ko) was also calculated using “Nicholson and Kochi’s method” and observed in the order: KoCoII > KoFeIII. The antimicrobial activities of two complexes were computed against E. coli, P. aeruginosa, B. cereus, S. aureus, whereas antifungal activities against C. Albicans and were contrasted with the standard drug “Gentamycin”.