Open AccessInvestigation of the Antioxidant and Antibacterial Activity of Novel Quercetin Derivatives
Author(s) -
Shaker A. N. Al-Jadaan,
Rita S. Elias,
A. A. Reham
Publication year - 2020
Publication title -
biointerface research in applied chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.216
H-Index - 11
ISSN - 2069-5837
DOI - 10.33263/briac106.73297336
Subject(s) - quercetin , bacillus cereus , dpph , antibacterial activity , chemistry , antioxidant , escherichia coli , staphylococcus aureus , biochemistry , biology , bacteria , gene , genetics
Our previous work involved the preparation and characterization of six quercetin derivatives, three of which were novel Schiff bases, while the fourth was a novel ionic salt of iodine. This study involved the investigation of the in vitro antioxidant activity against DPPH free radical as well as the in vitro antibacterial activity against Bacillus cereus, Salmonella spp., Escherichia coli and Staphylococcus aureus of quercetin and its 1-6 derivatives. The results revealed that all the studied quercetin derivatives had shown less antioxidant and antibacterial activity than quercetin itself, except that of compounds 3 and 4, which displayed an improvement in the antibacterial activity against Escherichia coli as compared to that of quercetin.