Open AccessTranslational readthrough at <i>F8</i> nonsense variants in the factor VIII B domain contributes to residual expression and lowers inhibitor association
Author(s) -
Maria Francesca Testa,
Silvia Lombardi,
Francesco Bernardi,
Mattia Ferrarese,
Donata Belvini,
Paolo Radossi,
Giancarlo Castaman,
Mirko Pinotti,
Alessio Branchini
Publication year - 2022
Publication title -
haematologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.782
H-Index - 142
eISSN - 1592-8721
pISSN - 0390-6078
DOI - 10.3324/haematol.2022.281279
Subject(s) - nonsense , nonsense mutation , missense mutation , biology , genetics , microbiology and biotechnology , genotype , phenotype , chemistry , gene